Comedian Paula Poundstone has been honing her standup routine since the late '70s. She appeared on Saturday Night Live when Robin Williams (her friend and mentor) hosted. And this is timely: In '92 she traded in typical standup for "something she thought would be more real with the audience and filed memorable field commentary of the presidential election for The Tonight Show with Jay Leno,” according to her bio. For most of the last decade, Poundstone’s her sharp wit and sharper observations have led her to National Public Radio’s Wait Wait ... Don't tell Me. Poundstone appears at Diana Wortham Theatre on Friday, Nov. 18. 8 p.m. $35 in advance or $38 day of show. http://www.dwtheatre.com.